21c Museum Hotel St Louis

Hotel Checkout

Reservations:

+1 (888) 385-8465

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From

$159

Reservations:

+1 (888) 385-8465

Hotel Highlights

Discover a stylish 4-star hotel experience in East Saint Louis, Illinois. The property sits at 1528 Locust Street, about 2.8mi from the city center, offering a convenient base for exploring the area.

Prices start from $159 per night, and the hotel has 905 reviews to date. Featured amenities include spa/wellness packages, pet-friendly accommodations (extra charges), a restaurant, an indoor swimming pool (free), free Wi‑Fi, room service, a fitness center, streaming service (like Netflix), steam room, spa, air conditioning, a bar, a terrace, soundproof rooms, a 24-hour front desk, non-smoking rooms, wheelchair accessibility, an elevator, a bathtub, and free toiletries.

Bedroom, Bed in 21c Museum Hotel St Louis

Rooms

Deluxe King Suite with Roll-In Shower - Accessible in 21c Museum Hotel St Louis

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1 King Size Bed

45 sqft

Deluxe Suite, King Bed, Mobility Accessible

Private Bathroom

Flat-screen TV

Streaming service (like Netflix)

Refrigerator

The air-conditioned suite has 1 bedroom and 1 bathroom with a walk-in shower and a hairdryer. The suite features a seating area, a wardrobe, a safe deposit box, heating and a flat-screen TV with streaming services. The unit has 1 bed.

Deluxe Double Queen Room with Roll-In Shower in 21c Museum Hotel St Louis

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2 Queen Size Beds

365 sqft

Deluxe Room, Queen Bed, Mobility Accessible

Private Bathroom

Flat-screen TV

Streaming service (like Netflix)

Refrigerator

Offering free toiletries and bathrobes, this quadruple room includes a private bathroom with a walk-in shower and a hairdryer. The quadruple room offers air conditioning, a seating area, a wardrobe, a safe deposit box and a flat-screen TV with streaming services. The unit offers 2 beds.

Loft with Two Queen Beds in 21c Museum Hotel St Louis

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2 Queen Size Beds

40 sqft

Room, 2 Queen Beds, Loft

Private Bathroom

Bathtub

Flat-screen TV

Streaming service (like Netflix)

Discover More

Practical touches include a 24-hour front desk, elevator access, air conditioning, a bathtub, free toiletries, soundproof rooms, non-smoking rooms, wheelchair accessibility, a terrace, and a bar, ensuring comfort and convenience for a memorable stay.

Wellness and leisure come easy with a complimentary indoor pool, a steam room, and spa/wellness packages designed to unwind after a day of exploring East Saint Louis.

Dining and social spaces shine with Idol Wolf, a Modern restaurant serving Spanish cuisine, plus a bar and terrace for relaxed evenings. Practical perks include free Wi‑Fi, room service, a fitness center, and a streaming service (like Netflix) for easy downtime; pets are welcome with possible charges.

Experience the Best

Convenience is built in with a 24-hour front desk, elevator access, air conditioning, a bathtub, free toiletries, soundproof rooms, and non-smoking rooms, ensuring a comfortable, hassle-free stay.