Facade/entrance in 21c Museum Hotel St Louis

21c Museum Hotel St Louis

Hotel Highlights

Welcome to the 21c Museum Hotel St. Louis, where contemporary art meets luxurious comfort! Located at 1528 Locust Street in East Saint Louis, this vibrant 4-star hotel is just 2.8mi from the hustle and bustle of the city center. Starting at just $134 per night, you can indulge in a unique experience that transforms your stay into a delightful journey through creativity and culture—all while having a fantastic time with friends or family!

Facade/entrance in 21c Museum Hotel St Louis
Property building in 21c Museum Hotel St Louis

Rooms

Luxury Queen Room in 21c Museum Hotel St Louis

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2 Queen Size Beds

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420 sqft

Luxury, 2 Queen Size Beds

Private Bathroom

Bathtub

Flat-screen TV

Streaming service (like Netflix)

Indulge in the spacious and luxurious Quadruple Luxury Queen Room with Two Queen Beds boasting 420 sqft of comfort. With amenities such as a private bathroom, flat-screen TV, and air conditioning, your stay will be nothing short of serene and enjoyable.

Deluxe Queen Room in 21c Museum Hotel St Louis

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2 Queen Size Beds

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365 sqft

Deluxe, 2 Queen Size Beds

Private Bathroom

Bathtub

Flat-screen TV

Streaming service (like Netflix)

Experience ultimate comfort in our spacious Deluxe Queen Room with Two Queen Beds, boasting a generous 366 sqft. This family-friendly room accommodates up to 4 adults and 3 children, offering a private bathroom, flat-screen TV, air conditioning, and all the necessary amenities for a perfect stay.

Deluxe Double Queen Room with Roll-In Shower in 21c Museum Hotel St Louis

Show 3 photos

2 Queen Size Beds

/

365 sqft

Deluxe, Queen Size, Accessible

Private Bathroom

Flat-screen TV

Streaming service (like Netflix)

Refrigerator

Offering free toiletries and bathrobes, this quadruple room includes a private bathroom with a walk-in shower and a hairdryer. The quadruple room offers air conditioning, a seating area, a wardrobe, a safe deposit box and a flat-screen TV with streaming services. The unit offers 2 beds.

Discover More

Step into a world of relaxation with our fantastic amenities, including an inviting indoor swimming pool and a rejuvenating spa with wellness packages that'll leave you feeling like royalty. With a fitness center at your convenience, you'll have no excuse not to stay active during your getaway. For food lovers, our on-site restaurant offers delicious bites to fuel your adventures, while the well-stocked bar is the perfect spot to unwind after exploring the local sights. Service is at the heart of what we do—enjoy 24-hour front desk assistance, room service, and even massage options for that extra pampering.

Lobby or reception in 21c Museum Hotel St Louis
Lobby or reception in 21c Museum Hotel St Louis

Experience the Best

Don't just take our word for it; with 654 enthusiastic reviews, guests rave about their experiences here, celebrating the unique combination of art, comfort, and stellar service. The soundproof rooms ensure a peaceful night’s sleep, while the terrace provides a lovely view of your surroundings. Come and discover why the 21c Museum Hotel St. Louis is not just a place to stay, but a true experience that infuses luxury with creativity!

Coffee/tea facilities in 21c Museum Hotel St Louis
Coffee/tea facilities in 21c Museum Hotel St Louis

Plan Your Stay

As you explore the 21c Museum Hotel St. Louis, prepare to be wowed by the exquisite dining experience awaiting you at our on-site restaurant, Idol Wolf. This modern eatery shines with Spanish flavors, infusing every dish with creativity and flair. Whether you're celebrating a special occasion or simply winding down after a day of exploration, your culinary adventure here will be a highlight of your stay. Pair your meal with a perfectly crafted cocktail from our well-stocked bar, where friendly bartenders are eager to bring your favorite concoctions to life.

Lounge or bar in 21c Museum Hotel St Louis
Restaurant/places to eat in 21c Museum Hotel St Louis

Amenities

Spa/Wellness packages

Restaurant

Indoor swimming pool

Business center

Room service

Fitness center

Streaming service (like Netflix)

Steam room

Fitness centre/facilities in 21c Museum Hotel St Louis
Fitness centre/facilities in 21c Museum Hotel St Louis

Pool

Indoor

All season,

Spa and wellness centre/facilities in 21c Museum Hotel St Louis
Spa and wellness centre/facilities in 21c Museum Hotel St Louis

Restaurant

Idol Wolf

Modern, Spanish

Breakfast in 21c Museum Hotel St Louis
Restaurant/places to eat in 21c Museum Hotel St Louis
Lobby or reception in 21c Museum Hotel St Louis
Found this hotel for a quick stay to celebrate our 20th anniversary. It was a great choice and a really unique and artsy place. Appreciated the extra effort to make it interesting. The fun wallpaper in the stair well was a good backdrop. We enjoyed visiting the art gallery and there was really nice work in there. An artist we had seen at the Nashville art museum previously had work in here. Fun bonus. The room was modern and clean and we loved the glass shower that gave it an extra wow factor. Didn't get to the pool or the billiards table but we did pickup breakfast from the little cafe on our way out and while the selection was pretty small, it was nice to have a little something before we left. The coffee with honey was really great.

Marci

The location was wonderful! We were in town for a concert at Busch Stadium. We were able to walk to to and from the concert, so we didn't have to mess around with finding parking near the stadium. The hotel was very clean and comfortable, and the staff was very friendly and helpful! The hotel itself is beautiful. Converted from a YMCA built in 1926, the facilities (especially the pool area and the lobby) and aesthetic are fantastic, especially if you enjoy historical buildings. Bonus win- there is a rubber ducky in the bathroom that you can take with you after your stay! My daughter named ours Louis! We will stay at this hotel again whenever we find ourselves in St. Louis!

Karin

Best indoor pool and hot tub I’ve ever had access to in a hotel — you could actually have a proper lap swim! Competitively priced for downtown. We parked on street (no trouble finding parking). Sorry we didn’t get to take full advantage of restaurant and bar and surrounding area— we were there for the eclipse and didn’t spend much time in St Louis itself. Nice to have a coffee shop in house. Good products in bathrooms (Malin & Goetz); comfy bed. Wish we had more time to check out the art gallery and loved idea of yoga in the gallery! I would definitely stay here again if we visit STL.

Barbara

This property is awesome the atmosphere was different in a good way you walk in the door up the stairs Art lobby was large and roomy. Friendly staff very warm and welcoming. The design is genius there something for everyone. Nice bar area, and it also has a nice lounge/ game room, restaurant, and let’s talk about the museum totally awesome local artist kudos. Rooms were comfortable the transformation from the old YMCA to this update beauty impressive. This is definitely a get away without the kidos for the first time then bring them back. Oh yea forgot about the outside patio

Carnita

The fact that the hotel is a museum is really cool, we enjoyed walking around and seeing all the art. The pool is really nice, it’s a decent sized pool and it wasn’t dirty or anything, there were toys from people the previous night but it didn’t bother me. The hot tub & saunas were really nice too. Location isn’t horrible, we had a concert at enterprise center and it was only a 10 min walk. The bar was really nice too, a little pricey but not bad.

Monica

Found this hotel for a quick stay to celebrate our 20th anniversary. It was a great choice and a really unique and artsy place. Appreciated the extra effort to make it interesting. The fun wallpaper in the stair well was a good backdrop. We enjoyed visiting the art gallery and there was really nice work in there. An artist we had seen at the Nashville art museum previously had work in here. Fun bonus. The room was modern and clean and we loved the glass shower that gave it an extra wow factor. Didn't get to the pool or the billiards table but we did pickup breakfast from the little cafe on our way out and while the selection was pretty small, it was nice to have a little something before we left. The coffee with honey was really great.

Marci

The location was wonderful! We were in town for a concert at Busch Stadium. We were able to walk to to and from the concert, so we didn't have to mess around with finding parking near the stadium. The hotel was very clean and comfortable, and the staff was very friendly and helpful! The hotel itself is beautiful. Converted from a YMCA built in 1926, the facilities (especially the pool area and the lobby) and aesthetic are fantastic, especially if you enjoy historical buildings. Bonus win- there is a rubber ducky in the bathroom that you can take with you after your stay! My daughter named ours Louis! We will stay at this hotel again whenever we find ourselves in St. Louis!

Karin

Best indoor pool and hot tub I’ve ever had access to in a hotel — you could actually have a proper lap swim! Competitively priced for downtown. We parked on street (no trouble finding parking). Sorry we didn’t get to take full advantage of restaurant and bar and surrounding area— we were there for the eclipse and didn’t spend much time in St Louis itself. Nice to have a coffee shop in house. Good products in bathrooms (Malin & Goetz); comfy bed. Wish we had more time to check out the art gallery and loved idea of yoga in the gallery! I would definitely stay here again if we visit STL.

Barbara

This property is awesome the atmosphere was different in a good way you walk in the door up the stairs Art lobby was large and roomy. Friendly staff very warm and welcoming. The design is genius there something for everyone. Nice bar area, and it also has a nice lounge/ game room, restaurant, and let’s talk about the museum totally awesome local artist kudos. Rooms were comfortable the transformation from the old YMCA to this update beauty impressive. This is definitely a get away without the kidos for the first time then bring them back. Oh yea forgot about the outside patio

Carnita

The fact that the hotel is a museum is really cool, we enjoyed walking around and seeing all the art. The pool is really nice, it’s a decent sized pool and it wasn’t dirty or anything, there were toys from people the previous night but it didn’t bother me. The hot tub & saunas were really nice too. Location isn’t horrible, we had a concert at enterprise center and it was only a 10 min walk. The bar was really nice too, a little pricey but not bad.

Monica

Found this hotel for a quick stay to celebrate our 20th anniversary. It was a great choice and a really unique and artsy place. Appreciated the extra effort to make it interesting. The fun wallpaper in the stair well was a good backdrop. We enjoyed visiting the art gallery and there was really nice work in there. An artist we had seen at the Nashville art museum previously had work in here. Fun bonus. The room was modern and clean and we loved the glass shower that gave it an extra wow factor. Didn't get to the pool or the billiards table but we did pickup breakfast from the little cafe on our way out and while the selection was pretty small, it was nice to have a little something before we left. The coffee with honey was really great.

Marci

The location was wonderful! We were in town for a concert at Busch Stadium. We were able to walk to to and from the concert, so we didn't have to mess around with finding parking near the stadium. The hotel was very clean and comfortable, and the staff was very friendly and helpful! The hotel itself is beautiful. Converted from a YMCA built in 1926, the facilities (especially the pool area and the lobby) and aesthetic are fantastic, especially if you enjoy historical buildings. Bonus win- there is a rubber ducky in the bathroom that you can take with you after your stay! My daughter named ours Louis! We will stay at this hotel again whenever we find ourselves in St. Louis!

Karin

Best indoor pool and hot tub I’ve ever had access to in a hotel — you could actually have a proper lap swim! Competitively priced for downtown. We parked on street (no trouble finding parking). Sorry we didn’t get to take full advantage of restaurant and bar and surrounding area— we were there for the eclipse and didn’t spend much time in St Louis itself. Nice to have a coffee shop in house. Good products in bathrooms (Malin & Goetz); comfy bed. Wish we had more time to check out the art gallery and loved idea of yoga in the gallery! I would definitely stay here again if we visit STL.

Barbara

This property is awesome the atmosphere was different in a good way you walk in the door up the stairs Art lobby was large and roomy. Friendly staff very warm and welcoming. The design is genius there something for everyone. Nice bar area, and it also has a nice lounge/ game room, restaurant, and let’s talk about the museum totally awesome local artist kudos. Rooms were comfortable the transformation from the old YMCA to this update beauty impressive. This is definitely a get away without the kidos for the first time then bring them back. Oh yea forgot about the outside patio

Carnita

The fact that the hotel is a museum is really cool, we enjoyed walking around and seeing all the art. The pool is really nice, it’s a decent sized pool and it wasn’t dirty or anything, there were toys from people the previous night but it didn’t bother me. The hot tub & saunas were really nice too. Location isn’t horrible, we had a concert at enterprise center and it was only a 10 min walk. The bar was really nice too, a little pricey but not bad.

Monica

Location

1528 Locust Street, Wellston, 63103, Missouri, United States

Reservations:

+1-833-728-2041

or
21c Museum Hotel St Louis